Differences in the inhibition activity of E. At the same time, Bcc strains of environmental origin showed a higher resistance toward inhibition than the Bcc strains with clinical (i.e. purpurea are the most active in the inhibition of Bcc strains, followed by bacteria isolated from the rhizospheric soil, and endophytes from stem/leaf compartment. Data obtained revealed that bacteria isolated from the roots of E. In this work, a panel of 151 (endophytic) bacteria isolated from three different compartments (rhizospheric soil, roots, and stem/leaves) of the medicinal plant Echinacea purpurea were tested (using the cross-streak method) for their ability to inhibit the growth of 10 Bcc strains. A source of such natural compounds is represented by medicinal plants and, in particular, by bacterial communities associated with these plants able to produce molecules with antimicrobial activity. For this reason, the research of new natural compounds able to inhibit the growth of Bcc strains has raised new interest during the last years. Preliminary data on antibacterial activity of Echinacea purpurea-associated bacterial communities against Burkholderia cepacia complex strains, opportunistic pathogens of Cystic Fibrosis patients.Ĭhiellini, Carolina Maida, Isabel Maggini, Valentina Bosi, Emanuele Mocali, Stefano Emiliani, Giovanni Perrin, Elena Firenzuoli, Fabio Mengoni, Alessio Fani, Renatoīurkholderia cepacia complex bacteria (Bcc) represent a serious threat for immune-compromised patient affected by Cystic Fibrosis (CF) since they are resistant to many substances and to most antibiotics.
The genealogy of the new strain, designated Pepty 695/ch-I is the following one: Pepty 695/S (ergotoxine producer) -> Pepty 695/ch (secoergoline producer) -> Pepty 695/ch-I (tetracyclic clavine producer). Most suitable for alkaloid production in submerged culture is an ammoncitrate/sucrose medium. The alkaloid fraction is composed of chanoclavine-I ( approximately 10%) and a mixture of agroclavine/elymoclavine (90%).
This strain accumulates substantial amounts of clavine alkaloids (2 g/l).
Schumann, B Erge, D Maier, W Gröger, DĪ new strain of Claviceps was isolated from a blokked mutant of Claviceps purpurea.
A new strain of Claviceps purpurea accumulating tetracyclic clavine alkaloids.
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